RIN-m5F

 
Species source: rat
Organ source: pancreas (islet of Langerhans); insulinoma; produces insulin and L-dopa-decarboxylase but not somato
Plasmid:
  • pCDNA3-v-Src
  • pCDNA3.1-eNOS
Culture/Media: RPMI 1640 Medium
Antibiotics:
  • Geneticin (G418) - 400μg/ml -
Reference:
  • J. R. Tejedo, G. M. Cahuana, R. Ramirez, M. Esbert, J. Jimenez, F. Sobrino and F. J. Bedoya 2004. Nitric Oxide triggers the PI3K/Akt survival pathway in insulin producing RINm5F cells by arousing Src to activate IRS-1